Micky van de Ven Brace Ends Everton's Run at Brand New Stadium
Micky van de Ven emerged as the initial backline player to net twice in a English top-flight game for Spurs since the Belgian defender in March 2013.
At a glance
Micky Van de Ven heads home two times in opening period
The home side's Jake O'Brien has equalizer ruled after VAR review
Pape Matar Sarr nets third in 89th minute
This loss is the Merseyside club's initial at their new ground
The Tottenham defender found the net on two occasions as Tottenham extended their winning streak in away games in the top division and delivered the Toffees their initial loss at their new home.
The Toffees were undefeated in their last five matches at their recently opened stadium at Bramley-Moore Dock, having left Goodison Park behind after more than a century at the conclusion of last season.
But Tottenham's leader the Dutchman pounced on two occasions from corners in the first half to put their impressive record at jeopardy, and they were unable to turn it around before the midfielder - assisted by ex-Everton forward Richarlison - headed home a final goal to put the game to bed.
The Everton defender thought he had equalized the scores a short while after the defender's first goal, glancing a bullet header past the Spurs keeper from an set-piece.
Beto, in the meantime, failed to convert a number of chances, while Vicario made a succession of fine saves to guarantee Tottenham went five matches on the road without defeat in the Premier League.
But the VAR intervened, advising the match official to check the goal on the pitchside monitor and the official decided that Jack Grealish and Iliman Ndiaye were in an illegal position and had interfered with the Spurs keeper.
The win moves Thomas Frank's team up to third in the division, a handful of points off local foes and leaders Arsenal.
The Merseyside club stay in 14th position and sit half a dozen points clear of the drop zone.
Tottenham analysis: Van de Ven fulfils duties at each end of the field
After a uninspiring midweek display in the Champions League against Monaco, where they mustered a mere two shots on target, Frank chose Randal Kolo Muani in attack instead of ex-Everton forward Richarlison.
The new arrival was failed to influence the game before being substituted for the substitute after an hour on the pitch, but it emerged he proved unnecessary in the end.
Defender the Dutchman transformed into an offensive threat to be feared.
Tottenham's first goal came from a cleverly executed set-piece play, with Rodrigo Bentancur heading the ball back across the six-yard box for an unmarked Van de Ven to score.
And the captain - stepping up as skipper in the Argentine's absence - added his second in first-half stoppage time as he outjumped the England keeper to nod in.
The Dutchman was just as outstanding in defence, partnering well with his defensive colleague as the pair handled excellently with the 34 crosses sent their way by Everton.
Everton analysis: Everton lacking finishing touch
The club's recent stadium had been a fortress, but it seems the freshness may have worn off somewhat and supporters flocked to the gates after Sarr's final goal for Spurs.
The end in Everton's winning streak at home will not be a massive concern for the manager, but their striker situation are.
The forward and Thierno Barry - the Everton's pair of recognised centre-forwards - had scored only a single goal combined before Sunday's match.
And they were unable to contribute to that miserable tally on a damp and dreary evening on Merseyside.
The striker's performance was epitomized when he chose to overhead kick a golden opportunity from near the goal, even with having room and time to readjust for a more conventional attempt that would have tested the keeper.
Barry, too, was unable to make an impact after coming on for the starter in the 65th minute.
It was not for a lack of opportunity. Most of the home side's offensive moves came through the winger and the forward, who relentlessly whipped dangerous balls into the Tottenham penalty area.
Upcoming fixtures for these two sides?
Everton: Moyes' men head to Sunderland in the top flight on Monday, 3 November at 8 PM.
Spurs: The London club go to Newcastle's ground on Wednesday, 29 October for their fourth-round League Cup tie against Newcastle.